Full title
Authors
Fahim Zaman, Sharath Chandra Chandupatla, Lajos Zsom, Kenneth Abreo, Gazi B. Zibari
Summary
The publication presents the case of a kidney-pancreas transplant patient who developed ganciclovir-resistant cytomegalovirus infection. Cytomegalovirus infection can be a particularly serious complication in transplant patients, as immunosuppressive therapy may lead to a more severe course of infection and may also compromise graft function.
The article focuses on the use of foscarnet, which may represent a therapeutic option in cases where CMV infection cannot be adequately controlled with ganciclovir treatment, or where resistance is suspected. The practical significance of this case report lies in highlighting the challenges of antiviral therapy in transplant patients, the importance of recognizing drug resistance, and the need to balance antiviral efficacy, the patient’s clinical condition, and the protection of transplanted organs when making treatment decisions.
